Manhattan plot

Level 3 Category

Definition

A type of scatter plot used in genome-wide association studies (GWAS) to display the significance of genetic variants across the genome.

Example Image

Reproduced from Journal of Alzheimer's Disease, 88(2), 787-798. https://doi.org/10.3233/JAD-220293. Licensed under CC BY-NC 4.0.

Writing Alternative Text

Describe the variables, the height and distribution of the points, and any notable peaks or regions that stand out from the background signal.

Example Alt Text

"Two Manhattan plots compare chromosome-wide association results for Alzheimer’s dementia in females and males. The x-axis lists chromosomes, and the y-axis shows negative log base 10 p values. In females, the tallest peak near the final chromosomes reaches about 10 and exceeds the upper threshold near 7.3. In males, most points remain below this threshold, with the highest peak near chromosome 7."