Volcano plot

Level 3 Category

Definition

A type of scatter plot commonly used in genomics and proteomics. It plots statistical significance (p-value) versus magnitude of change (fold change), highlighting which variables are both highly significant and strongly different.

Example Image

Reproduced from IEEE Access, vol. 9, pp. 26156-26167, 2021. https://doi.org/10.1109/ACCESS.2021.3054162. Licensed under CC BY 4.0.

Writing Alternative Text

Describe the variables, the spread of the points, regions that show large changes or high significance, and any prominent clusters or standout points.

Example Alt Text

"A volcano plot shows log 2-fold change on the x axis and negative log 10 p value on the y axis. Points form a dense central cluster near zero-fold change with wider spread toward both sides. Blue points on the left and orange points on the right indicate highly significant decreases and increases. Dashed threshold lines separate significant and non significant regions."